Fly direct into Dusseldorf (Weeze) airport, in the heart of the region with regular Ryanair flights. Flight time from UK approximately 1 hour and from Ireland approximately 1 hr 45 minutes.
Book with Rail Europe and travel with Eurostar (from London St Pancras, Ebsfleet or Ashford International) to Brussels Midi and change onto a train to Roosendaal. In Roosendaal you can catch a train to Arnhem and Nijmegen in the Lower Rhine.
Take your car using one of the ferry connections below or hire a car on arrival in the region. There are many companies to choose from including Hertz, Avis, Europcar and Sixt